021-51111890
购物车（）
sales@molnova.cn
P 22077
CAS No. 1247819-59-5
P 22077 ( P22077; P-22077; P 22077 )
产品货号. M11000 CAS No. 1247819-59-5
P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
纯度: >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥259 | 有现货 |
|
| 5MG | ￥421 | 有现货 |
|
| 10MG | ￥672 | 有现货 |
|
| 25MG | ￥1353 | 有现货 |
|
| 50MG | ￥2584 | 有现货 |
|
| 100MG | ￥3856 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称P 22077
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
-
产品描述P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
-
同义词P22077; P-22077; P 22077
-
通路Proteasome/Ubiquitin
-
靶点DUB
-
受体USP2; USP4; USP47; USP5; USP7
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number1247819-59-5
-
分子量315.32
-
分子式C12H7F2NO3S2
-
纯度>98%(HPLC)
-
溶解度DMSO: 63 mg/mL (199.79 mM)
-
SMILESCC(C1=CC([N+]([O-])=O)=C(SC2=CC=C(F)C=C2F)S1)=O
-
化学全称1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Tian X, et al. Assay Drug Dev Technol, 2011, 9(2), 165-173.
产品手册
关联产品
-
XL177A
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34?nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
-
P-50429
P-50429 (P50429, P 50429) is a potent, selective, covalent deubiquitinase USP7 (EC50=0.42 uM)/USP47 (EC50=1.0 uM) inhibitor.
-
USP30 inhibitor 18
USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 μM). USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination.
